| Première Classe Lyon Centre - Gare Part Dieu | 148 rm | from €49 | › |
| Campanile Lyon Centre - Gare Part Dieu | 171 rm | from €57 | › |
| Campanile Lyon Centre Berges du Rhône | 134 rm | from €47 | › |
| ibis Lyon Centre Perrache | 123 rm | from €55 | › |
| La Résidence | 67 rm | from €71 | › |
| Hotel Lyon-ouest | 102 rm | from €60 | › |
| Normandie | 39 rm | from €40 | › |
| Séjours & Affaires Park Lane | 88 rm | from €40 | › |
| Séjours & Affaires Lyon Saxe Gambetta | 65 rm | from €31 | › |
| ibis Styles Lyon Confluence | 95 rm | from €64 | › |
| Campanile Lyon Centre Gare Perrache Confluence | 87 rm | from €48 | › |
| Hotel Axotel Lyon | 130 rm | from €57 | › |
| Hotel du Simplon | 37 rm | from €57 | › |
| Hotel Ainay | 21 rm | from €41 | › |
| Hôtel Mercure Lyon Lumiere | 78 rm | from €73 | › |
| Hôtel Charlemagne | 117 rm | from €66 | › |
| Au Logis de Vendôme | 33 rm | from €76 | › |
| Saint-Vincent | 32 rm | from €61 | › |
| Kyriad Lyon Centre Croix Rousse | 50 rm | from €51 | › |
| Citadines Presqu'île Lyon | 116 rm | from €63 | › |
| des Artistes | 45 rm | from €84 | › |
| Warwick Reine Astrid Lyon | 88 rm | from €130 | › |
| Républik | 35 rm | from €69 | › |
| Radisson Blu Hotel, Lyon | 245 rm | from €106 | › |
| Sofitel Lyon Bellecour | 164 rm | from €127 | › |
| Mercure Lyon Centre Plaza République | 82 rm | from €96 | › |
| Mercure Lyon Centre Château Perrache | 120 rm | from €72 | › |
| Hotel Lyon Métropole | 174 rm | from €86 | › |
| Le Roosevelt | 48 rm | from €111 | › |
| Silky by HappyCulture | 41 rm | from €97 | › |
| Dock Ouest | 43 rm | from €60 | › |
| Séjours & Affaires Lyon Saint Nicolas | 38 rm | from €36 | › |
| Appart'City Confort Lyon Part Dieu | 140 rm | from €46 | › |
| Best Western Hotel de Verdun | 27 rm | from €85 | › |